What Supplements Should I Avoid With Autoimmune Disease?

The human body requires a plethora of nutrients for all of its systems to function properly on a cellular level. Most of the vitamins and minerals we require can be found in food, and typically, the best way to ensure you’re getting enough is to eat a well-rounded diet full of whole grains, fruits, vegetables, and lean protein sources.

The problem with eating healthily is that for many people, it’s just not feasible 100% of the time. Between busy lives and extensive options of delicious but not-so-great-for-you foods, it can be difficult to get all the nutrients you need through diet alone. This is why many people turn to supplements to help pick up the slack where their diet may be lacking.

While healthy people can benefit from most supplements if their body is low on certain things, those with chronic health issues such as autoimmune disease may not benefit from every supplement. In fact, some supplements can exacerbate certain conditions. If you have a chronic condition, you may be wondering, “What supplements should I avoid with autoimmune disease?” Read on to find out.

What is an autoimmune disease?

To understand what an autoimmune disease is, it’s important to understand how the immune system works. The immune system is the body’s first line of defense against pathogens and other foreign invaders that can cause illness. When a pathogen enters the body, immune cells spring into action in order to neutralize that threat.

A person with an autoimmune disease has a faulty immune system. Their immune response kicks into gear even when no threat is present and begins attacking the body’s own healthy cells, leading to cell damage. The cause of this reaction is unknown. Autoimmune diseases can affect any part of the body, and each type typically presents with its own symptoms and complications.

vitamin supplements
Image by Markus Spiske on Unsplash: What supplements should I avoid with autoimmune disease?

What can make an autoimmune disease worse?

As mentioned above, the exact cause of autoimmune disease isn’t yet known. However, there are a few factors that can actually increase the risk of a person developing one, or make the symptoms worse for people who do already have a type of autoimmune disease. Some things that can increase the risk of developing autoimmune disease include:

  • Smoking
  • Being related to someone with an autoimmune disease
  • Having one autoimmune disease already
  • Obesity
  • Infections

According to research, one of the biggest factors that can affect the worsening of an autoimmune disease or a flare-up in symptoms is stress. Certain medications have also been shown to play a role in the exacerbation of symptoms.

Do vitamins make autoimmune disease worse?

Since the immune system is revved up and attacking the body’s own tissues in someone who has an autoimmune disease, it’s thought that anything that makes the immune response stronger could end up making the autoimmune disease itself worse. This includes certain vitamins.

According to a report in the Sun Sentinel, high doses of anything that will “rev up” the immune system (such as vitamin C, beta carotene, cat’s claw, or echinacea) may actually be more harmful than helpful for people with autoimmune disease. However, research into specific vitamins has harbored different results. For example, studies on the use of vitamin C as an addition to formal treatment for autoimmune disease has found that, although it shouldn’t be used on its own, it can actually help regulate the immune pathways within the body.

Herbal supplements, on the other hand, have been shown to be detrimental to people with certain autoimmune diseases. One older study published in 2004 looked at the use of echinacea and algae spirulina in people with autoimmune disease and found that the use of these supplements actually caused a flare-up in symptoms. Other studies have corroborated this evidence, such as one published in 2021 that looked at how herbal supplementation using spirulina, chlorella, echinacea, and alfalfa affected autoimmune skin diseases. The study also found flare-ups and an increased immune response after use of the supplements.

Despite these findings, the situation may not be so cut and dry. For example, one vitamin supplement could help someone with a specific type of autoimmune disease while making symptoms worse in another. That is why it’s also important to speak to your doctor prior to taking any new supplements. They will be able to tell you what would be best to take for your specific condition.

vitamin supplements
Image by Michele Blackwell on Unsplash: Should I take vitamin D if I have autoimmune disease?

What supplements help autoimmune disease?

Research has been looking into certain vitamins and supplements that may be a welcome addition to a treatment plan for those with autoimmune disease, and has found that some vitamins could be helpful. One particular study examined the use of zinc and vitamin D in people with autoimmune disorders and found that these immune-regulating nutrients showed great promise in balancing immune function.

Other research has looked at supplements such as prebiotics and probiotics, fish oils, vitamin D, and curcumin as possible options when it comes to helping reduce disease flare-ups. The study found that each supplement could help in its own way when used to address a specific type of autoimmune disease. For example, prebiotics and probiotics may be helpful in treating inflammatory bowel disease; curcumin was also shown to be beneficial in people with ulcerative colitis, as well as rheumatoid arthritis.

These findings prove that, although supplements can help with autoimmune disease, the type of disease and supplement must be perfectly matched in order for the supplement to be a help rather than a hindrance. 

Featured image by Towfiqu barbhuiya on Unsplash

Can Thymosin α-1 Treat Symptoms Of Chronic Fatigue?

Chronic fatigue syndrome is characterized as extreme tiredness or fatigue that doesn’t get better with rest. The syndrome is unlikely to be attributed to an underlying medical condition, so it can be hard to pinpoint where it’s coming from and how it started in the first place. It is sometimes referred to as myalgic encephalomyelitis or systemic exertion intolerance disease.

Since the cause of chronic fatigue syndrome isn’t easy to determine, treatment options can also be difficult to attain. Some research suggests that the condition can be caused by various ailments, including viral infection or chronic stress. The only way to diagnose chronic fatigue syndrome is by ruling out other conditions, making the illness rather difficult to diagnose and treat.

Does chronic fatigue syndrome affect the immune system?

In people with chronic fatigue syndrome, the immune system can become compromised. This is because when chronic fatigue takes a hold of the body, it can lead to a prolonged immune response where none is needed. This results in the immune system attacking the body’s own healthy tissues.

Chronic fatigue syndrome is not an autoimmune disease per se, but it does share a significant amount of features with such conditions. Researchers believe that is affects the immune system in several ways, including the overproduction of cytokines; lowered ability of natural killer cells to defend against pathogens; and changes in T-cell activation.

Vital RX - depression
Image by Who Is Margot on Pixabay: Chronic fatigue is hard to diagnose, but people who suffer from the condition could benefit from thymosin alpha-1 treatment.

What is thymosin alpha-1?

Thymosin alpha-1 is a naturally occurring fragmented peptide. This means that is a smaller version of a protein molecule. It is made up of a 28-amino acid chain that is derived from a larger protein known as prothymosin α. It is created in tissues throughout the body, the most notable being the thymus gland.

Peptides such as thymosin alpha-1 are microscopic, but play vital roles in how well the body functions. They are the regulators of a myriad of specific bodily functions. The regulation of T-cells and immune response is thymosin alpha-1’s specific function. The thymus gland plays a big role in T-cell health as they grow; when they reach maturity, thymosin alpha-1 acts a cell signaler for the T-cells so that they know when to fight off pathogens.

What does thymosin do in the body?

Researchers have found many important processes can be affected by thymosin alpha-1. As mentioned above, one of the peptide’s biggest roles is to regulate and cell-signal for proper functioning of the immune system. It does this by directly affecting the action of the innate immune system in response to pathogens. It also regulates both the adaptive immune responses and the inflammatory response. The release of thymosin alpha-1 has been shown to increase lymphocytes to help the body ward off illness.

Thymosin alpha-1 also has the ability to heighten the body’s chances at fighting off infection. In one particular study on the effects of the peptide against COVID-19, researchers found that it could significantly reduce the risk of mortality of the viral infection by restoring T-cell numbers and reversing T-cell exhaustion.

Other conditions that have seen benefit from the use of thymosin alpha include:

  • Hepatitis B and C
  • HIV/AIDS
  • Some forms of cancer
  • Autoimmunity
  • Cystic fibrosis
  • Lyme disease
  • DiGeorge’s syndrome

For many conditions that require a boost in the immune function, thymosin alpha-1 has been an effective supplemental treatment.

Vital RX - immune cells
Image by Swift Science Writing on Pixabay: Immune cells are designed to fight off infection, but sometimes they need a little boost to do their job properly.

What are the benefits of taking a thymosin alpha-1 supplement? 

Because thymosin alpha-1 can help regulate and boost both immune and inflammatory processes, the benefits of supplementation can lead to a higher ability to fight off infection and avoid further illness.

When the peptide stimulates T-cells, it leads to an overall better response against viruses, bacteria, and tumor cells. It gives the immune response the boost it needs to become stronger against pathogens, which leads to a better immune function overall. It has also been shown to regulate inflammation caused by diseases such as rheumatoid arthritis, psoriatic arthritis, systemic lupus, and erythematosus. Other studies have shown that the peptide has the ability to increase the efficacy of vaccinations by supporting its ability to keep infection at bay.

Overall, the benefits that can be achieved by taking thymosin alpha-1 include:

  • Strengthened immune system
  • Lowering of widespread inflammation
  • Increase in the number and efficacy of T-cells
  • Eradication of damaged and unhealthy cells to hinder multiplication
  • Prevention of the spreading of disease throughout the body
  • Aid in recovery from chronic fatigue
  • Protection against oxidative stress

Other promising research has shown thymosin alpha-1 to be effective in treating a wide variety of cancers, although more study into the area will need to be conducted in terms of what it lacks when it comes to tumor targeting.  

Is thymosin alpha-1 safe?

Thymosin has been used in the treatment of viral infections and immune disorders for over four decades, and it is generally considered to be a safe and effective supplement for boosting immune function, warding off illnesses, and improving the symptoms of other chronic conditions.

Vital RX’s Immune Health Subscription Box includes thymosin alpha-1 to help boost immune function. Without a properly functioning immune system, the body is susceptible to chronic disease, illness, and infection, so if your system needs a boost, supplementation might be the answer.

Featured image by Dimitrisvetsikas1969 on Pixabay